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MOTS-c Nasal Spray

Research suggests that MOTS-c nasal spray is a mitochondrial peptide designed to help regulate metabolism and insulin action.

15ml Nasal Spray contains 10mg

30ml Nasal Spray contains 20mg

£39.78£74.57

SKU PG: Mots-C nasal Categories , ,

Description

MOTS-c Nasal Spray Spain   

Researchers think that MOTS-c nasal spray is a mitochondrial peptide that’s primary purpose is to control how insulin works and how the body uses energy. It is an MDP, which stands for “mitochondria-derived peptide.” It is written in the mitochondrial 12S rRNA as a sORF, or “short open reading frame.” MOTS-c nasal spray does many things in the body, like responding to stress and controlling the metabolism. For example, when there is metabolic stress, MOT-c can move to the nucleolus.

A study of sORFs in the 12rRNA found that 51 pairs translate into the MOTS-C, a 16-amino acid peptide that can go through putative translation changes (mitochondrial open reading frame of twelve S rRNA type c).
In one study, a microarray test was conducted on HEK293 cells treated with MOT-c; the results showed that MOT-c is a biologically active peptide. PCA showed that 72 hours after MOT-c treatment, there was a clear change in how genes were expressed globally (principal component analysis). A parametric study of gene set enrichment showed that gene expression changed significantly four hours after MOTS-c treatment and became clearer after 72 hours.

After MOTS-c treatment, the expression of genes involved in cell metabolism and inflammation differed. When the effects of MOTS-c on cellular metabolism were looked at, 194 of the 356 known metabolites were changed in a significant way by MOTS-c ST cells. 49 of these changes happened 24 hours after the MOTS-c ST treatment, and 177 of the changes happened 72 hours later. The pattern of the metabolites changed over time, and most biochemicals stayed the same at 24 and 72 hours.

There was a similarity between the metabolites that changed in MOTS-c ST and MOTS-c (exogenous synthetic MOTS-c). Most of the metabolites that changed in MOTS-c ST cells were also changed in MOTS-c cells that had been treated for 72 hours. Metabolite levels that were involved in purine and dipeptide metabolism kept going down, while acylcarnitine metabolism and the methionine cycle kept going up.

The research showed that the MOTS-c nasal spray could move into the nucleus to control the expression of nuclear genes. The AMPK (adenosine monophosphate-activated protein kinase) is triggered by metabolic stress, which causes the translocation of MOTS-c vial to the nucleus. MOTS-c peptide helps then helps the nucleus with cellular stress/ metabolic stress resistance. Once in the nucleus, peptide MOTS-c vial can combine with chromatin to regulate gene expression in the nucleus.

Benefits of Mots-C Nasal Spray Spain

Studies indicate that Mots-C Nasal Spray could offer the following benefits:

  • Enhances the liver’s ability to process fatty acids.
  • Enhances metabolic adaptability and balance.
  • Mitochondrial energy is regulated.
  • Has a protective effect against insulin resistance and obesity caused by ageing and poor nutrition.
  • Helps with weight loss.
  • Strengthens the body’s ability to withstand the effects of metabolic stress.
  • Exercise capability is increased.
  • Osteoporosis can be prevented.
  • Glucose levels are better controlled.
  • Cellular differentiation into osteoblasts is enhanced.

Amino Acid Sequence: MRWQEMGYIFYPRKLR
Molecular Formula: C101H152N28O22S2. C2HF3O2.

Mots-C Nasal Spray offers a convenient way of gaining all the advantages this peptide has to offer without the use of needles.

References:

https://www.sciencedirect.com/science/article/pii/S1550413118303905

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350682/

https://www.researchgate.net/publication/273122087_The_Mitochondrial-Derived_Peptide_MOTS-c_Promotes_Metabolic_Homeostasis_and_Reduces_Obesity_and_Insulin_Resistance

 

DISCLAIMER: We do not supply Peptides or Sarms to any individual under the age of 21. You must be a licensed and qualified healthcare practitioner. All products listed on this website (https://spa.pharmagrade.store) and provided through Pharma Grade Spain are intended ONLY FOR medical research purposes. Pharma Grade does not encourage or promote the use of any of these products in a personal capacity (i.e. human consumption) nor are the products intended as a drug, stimulant or for use in any food products.

 
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Additional information

size

15ml, 30ml

Certificates

MOTS-C_Pharmagrade HPLC Certificate

Disclaimer

We do not supply Peptides or Sarms to any individual under the age of 21. You must be a licensed and qualified healthcare practitioner. All products listed on this website (https://spa.pharmagrade.store) and provided through Pharma Grade are intended ONLY FOR medical research purposes. Pharma Grade does not encourage or promote the use of any of these products in a personal capacity (i.e. human consumption) nor are the products intended as a drug, stimulant or for use in any food products.